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Cialis Tadalafil (5mg) 28 Tablets

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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There are a few drug-food interactions that should be considered:

  • Grapefruit and Grapefruit Juice: Cialis can increase the blood pressure-lowering effects of the medication by>: Cialis can enhance the blood pressure-lowering effects of the medication, which can be dangerous for users of the drug.
  • High-Fat Meals: While Cialis may interact with Cialis users, consuming a high-fat breakfast or dinner before taking Cialis might enhance their sensitivity,ospital symptoms, or risk for side effects like headaches or increase heart rate.

C.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More About Cialis [Cialis] [Cialis Pills] [Translate]

As with most medications, Cialis can cause side effects. The most common side effects are:

More than 4 million prescriptions for Cialis were filled in the U. S. in 2017, accounting for 43% of all prescriptions. More than 13 million U. men received Cialis last year, accounting for about 15% of all prescriptions. More than a third of men who take Cialis experience side effects.

As with all prescription medications, Cialis can cause side effects.

Less than 3 million prescriptions for Cialis were filled in the U. More than a third of men who take Cialis cause heart problems.
  • Gastrointestinal problems
  • Fatigue

In rare cases, Cialis can cause more serious side effects, including:

  • Signs of liver problems
  • Blood disorders
  • Muscle or joint pain
  • Heart attack
  • stroke
  • Liver function tests can show that Cialis can cause side effects including:
  • Heart problems
  • Low blood pressure
  • Low testosterone
  • Severe allergic reactions

A federal judge ruled Thursday that a drugmaker that is marketing erectile dysfunction drug Cialis to consumers can sell the drug to physicians without the knowledge of its maker, Eli Lilly & Co., in the U. S. District Court for the Northern District of California.

The ruling, which is being appealed, was filed by the California Court of Appeal, which was reviewing the FDA's decision about the drugs' label changes in March, and the drugmaker's conduct in the drug's marketing.

The case was heard by U. District Judge Charles K. Geer in San Diego.

Under the judge's ruling, Cialis was being promoted for men with erectile dysfunction, which is a condition that may be present when a man is unable to achieve or maintain a firm erection sufficient for sexual intercourse.

"Erection is not a condition that requires sexual arousal," said federal judge in San Diego, who also ruled that Lilly had not demonstrated that the drug was medically necessary.

Cialis is currently sold under the brand name Viagra, which was approved in 1998 for erectile dysfunction. Lilly said that while the drug was approved for use by patients in 1999, the label changes meant that it could not be used by men whose erection was impeding the flow of sexual activity.

"While we have not seen these changes in the label, we do know that some of these side effects are related to Cialis," said Eli Lilly spokeswoman Cindy Eckert. "We do not know that the side effects associated with Cialis are related to this drug."

The FDA has not made a ruling on whether Cialis is medically necessary.

Lilly's marketing, which is to be made up entirely of a product, has been in the news for years. The company is trying to get a new product with the drug Cialis, which was first approved in 2003 and was promoted for use by men who suffer from erectile dysfunction.

The FDA did not comment on the decision, but reports that the drugmaker has been advertising the drug for more than 30 years.

Eckert said Lilly's ads for Cialis are not unusual for the drug's maker, Eli Lilly and Company, in marketing erectile dysfunction drugs to its own consumers.

"We're not aware of a large number of men who would be interested in the availability of erectile dysfunction drugs," said Eli Lilly spokeswoman Mary Jane Smith.

The FDA's ruling also gives Lilly the power to take action against the manufacturer of the drug, which is marketing the drug for use by patients who suffer from erectile dysfunction.

Lilly said in its statement that it "does not have sufficient information about the potential side effects associated with Cialis and does not believe that information should be considered confidential information to which consumers may object."

Lilly also did not respond to an email from the company's general counsel, Paul A. Guglielmi, who asked not to be identified.

Copyright 2024 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Originally Published: March 12, 2016 at 12:00 AM EST

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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